Zebrafish are increasingly swimming into the view of large-scale drug screening projects. Behavioral screens can be used as a first-line detection tool for new drug effects, and their popularity continues to grow. Translating results to what we might see in humans requires an appropriate (vertebrate) model suited for large-scale

studies. This is a tall order, but one zebrafish easily fill. Mice and rats are more established model systems, but size and cost are often prohibitive to large-scale analyses. Compromising in favor of size and cost points to an invertebrate model like Drosophila. However, in zebrafish researchers find the economy required for high throughput studies, in a vertebrate model.

Read the rest of this article on the Noldus Blog where it was originally posted.